A decisive element in the human cation channel TRPM2 is a region in its cytosolic C-terminus named NUDT9H because of its homology to the NUDT9 enzyme, a pyrophosphatase degrading ADP-ribose (ADPR).In hTRPM2, however, the NUDT9H domain has lost its enzymatic activity but serves as a binding domain for ADPR.As consequence of binding, gating of the ch
Background: The use of agricultural by-products as a source of functional ingredients, particularly those from crop plants, has received great Preorder interest.Banana (Musa spp.) is a common food crop worldwide, but its peel, similar to other agricultural by-products, is often discarded.Banana peel has the potential to be transformed into function
Measles, a highly contagious respiratory illness caused by the measles virus (MeV), poses significant global and national public health challenges despite advancements in vaccination efforts.Though measles was declared eliminated in the United States in 2000, recent years have seen a resurgence of cases, particularly in under-vaccinated communities